The first part of the presentation will delve into the forefront of Artificial Intelligence (AI) technologies pertinent to Agriculture 4.0. We will explore vital applications of AI that are instrumental in tackling challenges faced by the agriculture and food sectors, especially within the Global South. A showcase of a few research endeavors undertaken by researchers from the University of Florida, employing AI to advance agriculture and food systems, will also be shared as well principal challenges and promising opportunities lying ahead. The second part of the talk will outline lessons learned from deployment of digital tools for dairy farm assessment, formulating livestock rations, and marketing goats in African and Asian countries.